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Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface
oleh: Srinivas Abbina, Lily E. Takeuchi, Parambath Anilkumar, Kai Yu, Jason C. Rogalski, Rajesh A. Shenoi, Iren Constantinescu, Jayachandran N. Kizhakkedathu
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-06-01 |
Deskripsi
The blood circulation time is important to the biomedical application of nanomaterials. Here, the authors explore the effect of protein corona formation on the blood residency of nanomaterials and show circulation times are governed by the dynamic remodelling of protein opsonins in vivo.