MIR retrotransposons link the epigenome and the transcriptome of coding genes in acute myeloid leukemia

oleh: Aristeidis G. Telonis, Qin Yang, Hsuan-Ting Huang, Maria E. Figueroa

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

The links between DNA methylation and gene expression are poorly understood on large-scale. Here the authors show that MIR retrotransposons within introns can play this role in acute myeloid leukemia harbouring mutations in epigenetic modifiers.