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MIR retrotransposons link the epigenome and the transcriptome of coding genes in acute myeloid leukemia
oleh: Aristeidis G. Telonis, Qin Yang, Hsuan-Ting Huang, Maria E. Figueroa
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
The links between DNA methylation and gene expression are poorly understood on large-scale. Here the authors show that MIR retrotransposons within introns can play this role in acute myeloid leukemia harbouring mutations in epigenetic modifiers.