Sclerosing Variant of the Bronchioloalveolar Carcinoma: Imaging Findings in an Atypical Case

oleh: Carolina Lamas Constantino, Edson Marchiori, Gláucia Zanetti, Antonio Muccillo, Mariana Leite Pereira, Guilherme Abdalla, Pedro Martins, Nina Ventura, Rodrigo Canellas, Viviane Brandão, Romulo Varella de Oliveira

Format: Article
Diterbitkan: Wiley 2010-01-01

Deskripsi

Bronchioloalveolar carcinoma remains one of the most enigmatic lung cancers, demonstrating varied growth patterns, mixed histological features, and confusing clinical manifestations. This paper reports a case of an unusual form of presentation: a sclerosing type associated with desmoplastic reaction and cicatrization. A 75-year-old woman was admitted with persistent dry cough and progressive dyspnea. Physical examination showed bilateral inspiratory crackles. A chest radiograph and high-resolution computed tomography demonstrated confluent airspace nodules, forming areas of consolidation in both lungs, with signs of architectural distortion. The lung biopsy revealed a nonmucinous sclerosing bronchioloalveolar carcinoma.