A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts
oleh: Hibiki Vincent Tanaka, Nathaniel Chuen Yin Ng, Zhan Yang Yu, Martin Miguel Casco-Robles, Fumiaki Maruo, Panagiotis A. Tsonis, Chikafumi Chiba
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-03-01 |
Deskripsi
How limb regeneration in the newt is regulated at a cellular level is much debated. Here, the authors show different mechanisms acting at different developmental stages, namely stem/progenitor cells in larval regeneration and muscle fibres in the blastema regulate limb regeneration after metamorphosis.