Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin

oleh: Alexandra Friese, Alex C. Faesen, Pim J. Huis in ‘t Veld, Josef Fischböck, Daniel Prumbaum, Arsen Petrovic, Stefan Raunser, Franz Herzog, Andrea Musacchio

Format: Article
Diterbitkan: Nature Portfolio 2016-04-01

Deskripsi

SKAP and Astrin form a heterodimer that localizes to spindle microtubules and to mature microtubule-kinetochore attachments during mitosis. Here, the authors identify molecular requirements for the inter-subunit interaction of SKAP and Astrin and kinetochore recruitment.