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Objectives: The present review study aimed at investigating the vocational rehabilitation of individuals with drug dependence disorders.  Methods: Based on the research method, a comprehensive search was conducted in the following databases: PubMed, Scopus, Web of Science, Science Direct, EBSCO, ProQuest and Google Scholar. All keywords synonymous with vocational rehabilitation and substance abuse were considered in search. Then related studies with vocation rehabilitation were selected and included in the study. Results: Job is a protective and major factor in effective treatment, and ignoring vocational counseling and rehabilitation leads to a significant defect in addiction treatment.  Discussion: Individuals receiving vocational services along with drug abuse treatment would experience reduced drug abuse and a more productive life.