Phylogeny-guided genome mining of roseocin family lantibiotics to generate improved variants of roseocin
oleh: Sandeep Chaudhary, Shweta Kishen, Mangal Singh, Sunanda Jassal, Reeva Pathania, Kalpana Bisht, Dipti Sareen
| Format: | Article |
|---|---|
| Diterbitkan: | SpringerOpen 2023-03-01 |
Deskripsi
Keypoints Taxonomically distant species have a wide diversity of roseocin family lantibiotics. The phylogeny-guided approach opens new possibilities for RiPPs bioengineering. Bioactive variants of roseocin were generated using semi-in vitro reconstitution.