A phenotypic and genomics approach in a multi-ethnic cohort to subtype systemic lupus erythematosus
oleh: Cristina M. Lanata, Ishan Paranjpe, Joanne Nititham, Kimberly E. Taylor, Milena Gianfrancesco, Manish Paranjpe, Shan Andrews, Sharon A. Chung, Brooke Rhead, Lisa F. Barcellos, Laura Trupin, Patricia Katz, Maria Dall’Era, Jinoos Yazdany, Marina Sirota, Lindsey A. Criswell
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-08-01 |
Deskripsi
Systemic lupus erythematosus (SLE) is an autoimmune disease of substantial phenotypic heterogeneity in different ethnic groups. Here, using data from a multi-ethnic cohort, the authors describe an approach based on clinical and molecular data to subtype SLE patients into three clusters of severity.