Using Mice to Treat (Wo)men: Mining Genetic Changes in Patient Xenografts to Attack Breast Cancer
oleh: Steffi Oesterreich, Adam M. Brufsky, Nancy E. Davidson
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2013-09-01 |
Deskripsi
In this issue of Cell Reports, Li et al. show that the analysis of genetic changes in patient-derived xenografts can reveal crucial details of tumor evolution, such as the emergence of functional estrogen receptor mutations in endocrine-resistant breast cancer.