Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics

oleh: Frederik Van den Broeck, Senne Heeren, Ilse Maes, Mandy Sanders, James A. Cotton, Elisa Cupolillo, Eugenia Alvarez, Lineth Garcia, Maureen Tasia, Alice Marneffe, Jean-Claude Dujardin, Gert Van der Auwera

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2023-05-01

Deskripsi

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis–related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.