Enantioselective semireduction of allenes

oleh: Zhiwei Chen, Vy M. Dong

Format: Article
Diterbitkan: Nature Portfolio 2017-10-01

Deskripsi

Reduction of allenes poses several challenges in terms of chemo-, regio- and enantio-selectivity. Here, the authors report a rhodium-Josiphos catalytic system that reduces a variety of aryl allenes to chiral benzylic compounds with excellent selectivity and functional group tolerance.