Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma
oleh: Yun-Fan Sun, Liang Wu, Shi-Ping Liu, Miao-Miao Jiang, Bo Hu, Kai-Qian Zhou, Wei Guo, Yang Xu, Yu Zhong, Xiao-Rui Zhou, Ze-Fan Zhang, Geng Liu, Sheng Liu, Ying-Hong Shi, Yuan Ji, Min Du, Nan-Nan Li, Gui-Bo Li, Zhi-Kun Zhao, Xiao-Yun Huang, Li-Qin Xu, Qi-Chao Yu, David H. Peng, Shuang-Jian Qiu, Hui-Chuan Sun, Michael Dean, Xiang-Dong Wang, Wen-Yuan Chung, Ashley R. Dennison, Jian Zhou, Yong Hou, Jia Fan, Xin-Rong Yang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-07-01 |
Deskripsi
Circulating tumour cells can be useful for monitoring disease progression but how they survive in the circulatory system is unclear. Here, the authors use single-cell sequencing of circulating tumour cells from multiple vascular sites in liver cancer patients and identify genes that may help the cells survive.