Strain level microbial detection and quantification with applications to single cell metagenomics
oleh: Kaiyuan Zhu, Alejandro A. Schäffer, Welles Robinson, Junyan Xu, Eytan Ruppin, A. Funda Ergun, Yuzhen Ye, S. Cenk Sahinalp
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Here the authors develop CAMMiQ, a combinatorial optimization approach that utilizes variable length, “unique” and “doubly-unique” genomic segments, showing improves identification and quantification of distinct microbes in metagenomic sequence data.