Simultaneous <i>Hodgkin′s disease</i> and kaposi sarcoma in a renal transplant recipient
oleh: Yaich S, Zagdane S, Charfeddine K, Hssairi D, Hachicha J
| Format: | Article |
|---|---|
| Diterbitkan: | Wolters Kluwer Medknow Publications 2010-01-01 |
Deskripsi
A 38-year-old women underwent first cadaver kidney transplantation. Her panel re-active antibody was 0%, and she had never previously been transfused nor pregnant. She received induction therapy with antithymoglobulin (ATG) as standard protocol and maintained on immuno-suppressive treatment of cyclosporine A, mycophenolate mofetil (MMF), and prednisone. Nine months after transplantation, she presented with anorexia, asthenia and weight loss. Cutaneous Ka-posi′s sarcoma and a Hodgkin disease were diagnosed. MMF was discontinued and cyclosporin A was switched to sirolimus. She also received a poly-chemotherapy associated with 4 courses of rituximab. Twelve months later, the patient had normal graft function and both malignancies were in complete remission.