Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
A Heart Rate Step Function Response Method for the Evaluation of Pulse Wave Velocity as a Predictor of Major Adverse Cardio-Vascular Events
oleh: Ioana Marin, Florina Georgeta Popescu, Elena-Ana Pauncu, Adrian Apostol, Viviana Mihaela Ivan, Catalin Nicolae Marin, Ovidiu Fira-Mladinescu, Sorin Ursoniu
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2022-11-01 |
Deskripsi
<i>Background and Objectives</i>: Cardiovascular diseases are the main cause of death worldwide, and pulse wave velocity (PWV) is considered a predictor of major adverse cardiovascular events. The study intended to be helpful in finding methods for the preliminary assessment of PWV in primary care units. <i>Materials and Methods</i>: The study group consisted of 36 subjects (considered healthy by their own statement) from the medical field (medicine students and residents) aged between 20 and 30 years: 33.3% males and 66.7% females. Two types of measurements were carried out successively: (a) measurements with the arteriograph and (b) measurements on a treadmill effort testing system, where heart rate (HR) was measured over time as a response to step function physical effort (PE). <i>Results</i>: The study allowed for the highlighting of some limits which, if exceeded, can be associated with high PWV values: (i) if after a moderate PE and a resting time of at least 6 min, the HR is larger than 80 b/min; (ii) if the relaxation time in a PE test of moderate intensity is larger than 1 min; (iii) if the HR measured after the subject is raised from the supine to orthostatic position is larger than 100 b/min, and (iv) if the resting HR is larger than 80 b/min. <i>Conclusions</i>: Steady-state HR correlates with PWV and may be used for the preliminary assessment of PWV.