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Renal angiomyolipomas (RMLs) can occur sporadically as solitary tumors or can be associated with tuberous sclerosis and present as bilateral multifocal disease. Modern radiographic imaging with ultrasonography (USG) or computed tomography (CT) scan can often diagnose this lesion based on its characteristic fat content. Even though it is a benign lesion, angiomyolipomas (AMLs) can be associated with symptoms, abdominal lump, and in some cases hemorrhage. Most can be managed with nephron-sparing approaches that include observation, angiographic embolization, or partial nephrectomy. The uniqueness of our article is that we successfully treated giant RML by angiography with selective renal angioembolization (RAE).