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As air pollution becomes progressively more serious, accurate identification of urban air pollution characteristics and associated pollutant transport mechanisms helps to effectively control and alleviate air pollution. This paper investigates the pollution characteristics, transport pathways, and potential sources of PM_2.5 in Weifang based on PM_2.5 monitoring data from 2015 to 2016 using three methods: Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT), the potential source contribution function (PSCF), and concentration weighted trajectory (CWT). The results show the following: (1) Air pollution in Weifang was severe from 2015 to 2016, and the annual average PM_2.5 concentration was more than twice the national air quality second-level standard (35 μg/m³). (2) Seasonal transport pathways of PM_2.5 vary significantly: in winter, spring and autumn, airflow from the northwest and north directions accounts for a large proportion; in contrast, in summer, warm-humid airflows from the ocean in the southeastern direction dominate with scattered characteristics. (3) The PSCF and CWT results share generally similar characteristics in the seasonal distributions of source areas, which demonstrate the credibility and accuracy of the analysis results. (4) More attention should be paid to short-distance transport from the surrounding areas of Weifang, and a joint pollution prevention and control mechanism is critical for controlling regional pollution.