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Background: Despite the growth in the number of studies on gambling disorders (GDs) and the potentially severe harm it may cause, problem gambling in older adults is rarely apparent in literature. Driven by the need to overcome this limitation, a broad systematic review is essential to cover the studies that have already assessed the determinants of GD in the elderly.Objectives: The aim of this systematic review is to understand the determinants related to GDs in elderly people.Methods: A total of 51 studies met the inclusion criteria, and data were synthesized.Results: Three major types of determinants were identified in this review: individual, socio-financial and environmental.Conclusions: This review explored the determinants influencing GDs in older people. The findings are relevant to academics, policymakers, patients, and practitioners interested in the identification and prevention of GD in older people.