Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

oleh: Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai, Motao Zhu, Changsheng Xing, Peng Tan, Meng Lin, Jian Wu, Jian Li, Mingjun Wang, Helen Y. Wang, Xin-zhuan Su, Rong-Fu Wang

Format: Article
Diterbitkan: Nature Portfolio 2018-11-01

Deskripsi

The inflammasome is an essential component of inflammatory processes and the host response to infection. Here the authors show that inflammasome activation modulates MyD88-IRF7 type I IFN signalling and anti-malaria immunity.