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Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity
oleh: Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai, Motao Zhu, Changsheng Xing, Peng Tan, Meng Lin, Jian Wu, Jian Li, Mingjun Wang, Helen Y. Wang, Xin-zhuan Su, Rong-Fu Wang
Format: | Article |
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Diterbitkan: | Nature Portfolio 2018-11-01 |
Deskripsi
The inflammasome is an essential component of inflammatory processes and the host response to infection. Here the authors show that inflammasome activation modulates MyD88-IRF7 type I IFN signalling and anti-malaria immunity.