Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells
oleh: Noelia Madroñal, José M. Delgado-García, Azahara Fernández-Guizán, Jayanta Chatterjee, Maja Köhn, Camilla Mattucci, Apar Jain, Theodoros Tsetsenis, Anna Illarionova, Valery Grinevich, Cornelius T. Gross, Agnès Gruart
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-03-01 |
Deskripsi
Dentate gyrus (DG) is critical for memory formation in the hippocampus but its role in memory retrieval is unclear. Here, Gross and colleagues, show that granule cells in DG are not required for memory retrieval but for maintenance, and inhibiting them with a drug leads to rapid loss of memory.