FTO-dependent m6A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke
oleh: Bin Li, Wen Xi, Ying Bai, Xue Liu, Yuan Zhang, Lu Li, Liang Bian, Chenchen Liu, Ying Tang, Ling Shen, Li Yang, Xiaochun Gu, Jian Xie, Zhongqiu Zhou, Yu Wang, Xiaoyu Yu, Jianhong Wang, Jie Chao, Bing Han, Honghong Yao
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
The mechanisms behind how vascular repair is regulated after ischemic stroke are yet to be elucidated. Here, the authors describe that a circular RNA interacts with FTO to promote vascular repair following stroke in mice and primates via mediating m6 A modification.