Time-dependent assessment of stimulus-evoked regional dopamine release
oleh: Rachel N. Lippert, Anna Lena Cremer, Sharmili Edwin Thanarajah, Clio Korn, Thomas Jahans-Price, Lauren M. Burgeno, Marc Tittgemeyer, Jens C. Brüning, Mark E. Walton, Heiko Backes
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-01-01 |
Deskripsi
It has proven difficult to measure the release of neurotransmitters, such as dopamine, in the human brain. Here, the authors introduce and validate a new method that infers dopamine release based on minute-by-minute fluctuations of the positron emission tomography (PET) radioligand [11C]raclopride.