PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus
oleh: Sarah Charnaud, Jacob E. Munro, Lucie Semenec, Ramin Mazhari, Jessica Brewster, Caitlin Bourke, Shazia Ruybal-Pesántez, Robert James, Dulcie Lautu-Gumal, Harin Karunajeewa, Ivo Mueller, Melanie Bahlo
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-02-01 |
Deskripsi
PLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands.