Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers
oleh: Wenpeng Zhang, Donghui Zhang, Qinhua Chen, Junhan Wu, Zheng Ouyang, Yu Xia
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-01-01 |
Deskripsi
Mass spectrometry is widely used for large-scale lipid profiling but distinguishing unsaturated lipid isomers is still challenging. Here, the authors present an analytical platform for high-throughput identification of lipid C=C location isomers in clinical samples, showing that isomer ratios may guide biomarker discovery.