Combinatorial hydrogels with biochemical gradients for screening 3D cellular microenvironments

oleh: Sebastián L. Vega, Mi Y. Kwon, Kwang Hoon Song, Chao Wang, Robert L. Mauck, Lin Han, Jason A. Burdick

Format: Article
Diterbitkan: Nature Portfolio 2018-02-01

Deskripsi

Tools to investigate a wide range of 3D microenvironmental parameters are important for understanding and controlling cell fate. Here, the authors develop hydrogels with orthogonal biochemical gradients and use this screening system to identify microenvironments that induce mesenchymal stem cell chondrogenesis.