Growth Hormone Deficiency Is Frequent After Recent Stroke
oleh: Thomas Lillicrap, Carlos Garcia-Esperon, Frederick Rohan Walker, Lin Kooi Ong, Michael Nilsson, Neil Spratt, Neil Spratt, Christopher R. Levi, Christopher R. Levi, Mark Parsons, Mark Parsons, Jörgen Isgaard, Jörgen Isgaard, Andrew Bivard, Andrew Bivard
| Format: | Article |
|---|---|
| Diterbitkan: | Frontiers Media S.A. 2018-09-01 |
Deskripsi
Introduction: The incidence of pituitary dysfunction after severe ischemic stroke is unknown, however given the increasing attention to pituitary dysfunction after neurological injuries such as traumatic brain injury, this may represent a novel area of research in stroke.Methods: We perform an arginine and human growth hormone releasing hormone challenge on ischemic stroke patients within a week of symptom onset.Results: Over the study period, 13 patients were successfully tested within a week of stroke (baseline NIHSS 10, range 7–16). Overall, 9(69%) patients had a poor response, with 7(54%) of these patients meeting the criteria for had human growth hormone deficiency. Other measures of pituitary function were within normal ranges.Conclusion: After major ischemic stroke, low GH levels are common and may play a role in stroke recovery.