Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Phenotypes on demand via switchable target protein degradation in multicellular organisms
oleh: Frederik Faden, Thomas Ramezani, Stefan Mielke, Isabel Almudi, Knud Nairz, Marceli S. Froehlich, Jörg Höckendorff, Wolfgang Brandt, Wolfgang Hoehenwarter, R. Jürgen Dohmen, Arp Schnittger, Nico Dissmeyer
Format: | Article |
---|---|
Diterbitkan: | Nature Portfolio 2016-07-01 |
Deskripsi
Switching target protein accumulation and activity by portable conditional degrons is potentially useful for both basic research and bioengineering. Here the authors present a versatile system to tune protein levels in live animals and plants using a temperature-sensitive N-end rule degradation signal.