Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
oleh: Timothy P. Lippert, Paulina Marzec, Aurora I. Idilli, Grzegorz Sarek, Aleksandra Vancevska, Mark Bower, Paul J. Farrell, Päivi M. Ojala, Niklas Feldhahn, Simon J. Boulton
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
~15% of cancers induce alternative lengthening of telomeres (ALT) to activate telomere maintenance. Here, the authors reveal that infection with Kaposi’s sarcoma herpesvirus (KSHV) induces acquisition of ALT-like features in previously non-ALT cell lines.