Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq
oleh: Felix M. Dobbs, Patrick van Eijk, Mick D. Fellows, Luisa Loiacono, Roberto Nitsch, Simon H. Reed
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-07-01 |
Deskripsi
Understanding how DNA double strand breaks (DSBs) form and are repaired in the genome depends on their accurate measurement. Here the authors describe INDUCE-seq; a DSB-detection method that simultaneously measures physiological and induced breaks throughout the genome.