Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
oleh: Marcin Kierczak, Nima Rafati, Julia Höglund, Hadrien Gourlé, Valeria Lo Faro, Daniel Schmitz, Weronica E. Ek, Ulf Gyllensten, Stefan Enroth, Diana Ekman, Björn Nystedt, Torgny Karlsson, Åsa Johansson
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
Despite the success of genome-wide association studies, much of the genetic contribution to complex traits remains unexplained. Here, the authors identify effects by rare variants on plasma proteins, and estimate the contribution of rare variants to the heritability.