The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19

oleh: Martina Di Maro, Mauro Cataldi, Mariarosaria Santillo, Martina Chiurazzi, Simona Damiano, Barbara De Conno, Antonio Colantuoni, Bruna Guida

Format: Article
Diterbitkan: Frontiers Media S.A. 2021-05-01

Deskripsi

The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We will show how studies performed on this disease are starting to provide evidence that these two anti-inflammatory systems may functionally interact with each other, a mechanism that could have a more general physiological relevance than only COVID-19 infection.