A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
oleh: Sudip Das, Eric Bernasconi, Angela Koutsokera, Daniel-Adrien Wurlod, Vishwachi Tripathi, Germán Bonilla-Rosso, John-David Aubert, Marie-France Derkenne, Louis Mercier, Céline Pattaroni, Alexis Rapin, Christophe von Garnier, Benjamin J. Marsland, Philipp Engel, Laurent P. Nicod
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
Here, the authors combine 16 S rRNA sequencing, culture and bioinformatics to profile the microbiome in 234 serial bronchoalveolar lavage samples from 64 lung transplant recipients collected over 49-months and identify distinct compositional states, termed pneumotypes, linked to current health status, and establish a collection of primary lung bacterial isolates, LuMiCol.