Structure of the Arabidopsis guard cell anion channel SLAC1 suggests activation mechanism by phosphorylation
oleh: Yawen Li, Yinan Ding, Lili Qu, Xinru Li, Qinxuan Lai, Pingxia Zhao, Yongxiang Gao, Chengbin Xiang, Chunlei Cang, Xin Liu, Linfeng Sun
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
The anion channel SLAC1 controls stomatal closure upon phosphoactivation. Here via structural analysis and electrophysiology, the authors propose an inhibition-release model where phosphorylation causes dissociation of a cytosolic plug from the SLAC1 transmembrane domains to induce conformational change in the pore-forming helices.