KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

oleh: Julia Neitzel, Nicolai Franzmeier, Anna Rubinski, Martin Dichgans, Matthias Brendel, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Rainer Malik, Michael Ewers

Format: Article
Diterbitkan: Nature Portfolio 2021-06-01

Deskripsi

The KL-VS haplotype of the Klotho gene has been associated with reduced risk of Alzheimer’s disease and dementia. Here the authors show an association between the KL-VS haplotype and amyloid-dependent tau accumulation using PET data.