Machine Learning Prediction and Experimental Validation of Antigenic Drift in H3 Influenza A Viruses in Swine

oleh: Michael A. Zeller, Phillip C. Gauger, Zebulun W. Arendsee, Carine K. Souza, Amy L. Vincent, Tavis K. Anderson

Format: Article
Diterbitkan: American Society for Microbiology 2021-04-01

Deskripsi

Influenza A viruses (IAV) in swine constitute a major economic burden to an important global agricultural sector, impact food security, and are a public health threat. Despite significant improvement in surveillance for IAV in swine over the past 10 years, sequence data have not been integrated into a systematic vaccine strain selection process for predicting antigenic phenotype and identifying determinants of antigenic drift.