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Parkinson's disease (PD) is a common neurodegenerative disease in the middle-aged and the elderly. Symptoms of autonomic dysfunction are frequently seen in PD patients, severely affecting the quality of life. This review summarizes research progress on the epidemiology, clinical manifestations, treatment principle, and the significance in early diagnosis and differential diagnosis of autonomic dysfunction in PD patients which helps to the early diagnosis and comprehensive management of PD. DOI: 10.3969/j.issn.1672-6731.2019.05.012