High-throughput immune repertoire analysis with IGoR

oleh: Quentin Marcou, Thierry Mora, Aleksandra M. Walczak

Format: Article
Diterbitkan: Nature Portfolio 2018-02-01

Deskripsi

B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.