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COVID-19 in renal transplant patients – A narrative review
oleh: Jayesh Valecha, Vasu Gupta, Vaidehi Mendpara, Carson Eric Snyder, Fnu Anamika, Kinna Parikh, Talha Mahmood, Shreya Garg, Rohit Jain
Format: | Article |
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Diterbitkan: | Wolters Kluwer Medknow Publications 2023-01-01 |
Deskripsi
The World Health Organisation declared the novel coronavirus known as severe acute respiratory syndrome coronavirus 2 a pandemic in March 2020. This virus has led to the deaths of more than 6 million people worldwide. Besides causing pneumonia, COVID-19 is linked to multiple organ dysfunction, including the kidneys, especially in individuals whose immune systems are already compromised. Consequently, individuals who are currently on a waiting list for a kidney transplant or who have recently received a kidney transplant are at a significantly increased risk for developing acute kidney injury and are severely impacted by the COVID-19 infection. The pandemic has negatively affected the transplantation process and led to a decrease in the number of organ donations as well as the volume of renal transplants. This review summarises the outcomes of COVID-19 infection in renal transplant patients, its pathophysiology, the challenges faced by the transplant community, and the management of immunosuppression.