Multi-responsive chitosan-based hydrogels for controlled release of vincristine

oleh: Bahareh Farasati Far, Mohsen Omrani, Mohammad Reza Naimi Jamal, Shahrzad Javanshir

Format: Article
Diterbitkan: Nature Portfolio 2023-02-01

Deskripsi

Hydrogels exhibit advantageous biocompatibility as carriers of chemotherapeutic agents, and those composed of natural polymers such as chitosan additionally offer biodegradability, environmental benefits, and low cost. Here, the authors develop highly swellable bio-hydrogels consisting of chitosan-graft-glycerol and carboxymethyl chitosan-graft-glycerol for sustained and pH-controlled anticancer vincristine sulfate release.