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Objective To explore the teaching effects of paper presentation in physiology. Methods 179 undergraduate students were selected from Jining Medical College as the research object and divided into the experiment group using the teaching method of paper presentation,and control group using the traditional lecture based learning teaching methods. At the end of the curriculum, an examination and a questionnaire were used to evaluate the teaching effects of students in the two groups. Results The performance of the students in the experiment group was statistically better than the control group (P＜0.05,P＜0.01)in terms of learning capacity and reasoning logic and capacity to solve problems. Conclusions In the physiology teaching, the paper presentation method is superior to the traditional method.