Antibiotic Susceptibility Monitoring of Neisseria gonorrhoeae in Bacolod City, Philippines

oleh: Clark Martin P. Araneta, Alain C. Juayang, Joseph Peter T. Lim, Eleeza Marie G. Quilop, Nadine Joy G. Casaysay, Gene Marie L. Tamesis, Tricia Marie G. Yude, Sarah Joyce E. Romero, Raziel C. Gayoba

Format: Article
Diterbitkan: MDPI AG 2017-08-01

Deskripsi

A local study was conducted to monitor the antibiotic susceptibility of N. gonorrhoeae in Bacolod City, Philippines. A total of 88 isolates were taken during the period of 1 January 2015 to 30 June 2017, from male patients ages 12 to 72 years. The highest incidence of gonorrhea infection was in the group aged 20–24 years (34.09%). The susceptibility pattern to antibiotics was as follows: ceftriaxone 100%, cefixime 82.6%, spectinomycin 92.1%, ciprofloxacin 4.9%, tetracycline 5.1%, and penicillin G with 0%. All isolates were noted to produce beta-lactamase, which can be attributed to plasmid-mediated penicillin resistance. These findings indicate that the resistance rates of N. gonorrhoeae to most commonly-used antibiotics are increasing, and that ceftriaxone remains an effective antibiotic in treating gonorrhea infections locally.