Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A

oleh: Qiao Li, Chen Zhuang, Donghua Wang, Wei Zhang, Rongxuan Jia, Fengxia Sun, Yilin Zhang, Yunfei Du

Format: Article
Diterbitkan: Beilstein-Institut 2019-12-01

Deskripsi

The construction of the biologically interesting chromone skeleton was realized by PhIO-mediated dehydrogenation of chromanones under mild conditions. Interestingly, this method also found application in the synthesis of the naturally occurring frutinone A.