Correlation between mitochondrial dysfunction and the pathogenesis of Parkinson's disease

oleh: Xiao-yu LIU, Jian-qing DING

Format: Article
Diterbitkan: Tianjin Huanhu Hospital 2014-02-01

Deskripsi

Parkinson's disease (PD) is a progressive neurodegenerative disease. A growing number of studies have shown that mitochondrial dysfunction plays an important role in the pathogenesis of PD. Therefore, this review will mainly discuss the research progress on the correlation between PD and abnormal mitochondrial dynamics, mitochondrial autophapy as well as mitochondrial DNA mutations and mitochondrial complex Ⅰ inhibition.<br />doi:10.3969/j.issn.1672-6731.2014.02.012<br />