Chromosome fragility in Freemartin cattle
oleh: V. Barbieri, L. Iannuzzi, G. P. Di Meo, G. Beneduce, R. Buonerba, S. Albarella, V. Peretti, F. Ciotola
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2010-04-01 |
Deskripsi
The aim of the present study was to verify chromosome fragility in freemartin cattle using chromosome aberration (CA) and sister chromatid exchange (SCE) tests. A total of eighteen co-twins were investigated. Fourteen animals were identified as cytogenetically chimeric (2n=60, XX/XY) while 4 were classified as normal. Freemartin cattle showed a higher percentage of aneuploid cells (18.64%) and highly significant statistical differences (P < 0.001) in mean values of gaps (4.53 ± 2.05), chromatid breaks (0.26 ± 0.51), and significant statistical differences (P < 0.005) in mean values of chromosome breaks (0.12 ± 0.43) when compared to 10 control animals from single births (aneuploid cells, 11.20%; gaps, 2.01 ± 1.42; chromatid breaks, 0.05 ± 0.22; chromosome breaks, 0.02 ± 0.14).