Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
oleh: Natalie M. Niemi, Gary M. Wilson, Katherine A. Overmyer, F.-Nora Vögtle, Lisa Myketin, Danielle C. Lohman, Kathryn L. Schueler, Alan D. Attie, Chris Meisinger, Joshua J. Coon, David J. Pagliarini
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-07-01 |
Deskripsi
The mitochondria houses several phosphatases, but their function is not well characterized. Here, the authors show that mitochondrial phosphatase Pptc7 is important during development for proper mitochondrial function and has a role regulating protein import with the translocase subunit Timm50.