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Space-time network coding (STNC) is a time-division multiple access (TDMA)-based scheme that combines network coding and space-time coding by allowing relay nodes to combine the information received from different source nodes during the transmission phase and to forward the combined signal to a destination node in the relaying phase. However, STNC schemes require all the relay nodes to overhear the signals transmitted from all the source nodes in the network. They also require a large number of timeslots to achieve full diversity in a multipoint-to-multipoint transmission. Both conditions are particularly challenging for large cellular networks where, assuming a downlink transmission, base stations (BSs) and users only overhear a subset of all the BSs. In this paper, we exploit basic knowledge of the network topology in order to reduce the number of time-slots by allowing simultaneous transmissions from those BSs that do not overhear each other. Our results show that these topology-aware schemes are able to increase the spectral efficiency per time-slot and bit error rate with unequal transmit power and channel conditions.