Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells
oleh: Minchul Kim, Vedran Franke, Bettina Brandt, Elijah D. Lowenstein, Verena Schöwel, Simone Spuler, Altuna Akalin, Carmen Birchmeier
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-12-01 |
Deskripsi
The transcriptional programs of nuclei in the muscle syncytium were assumed to be homogenous except at the neuromuscular and myotendinous junctions. Here, using single-nucleus transcriptomics, the authors reveal a previously unrecognized diversity and dynamics of myonuclear transcriptional programs.