Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
oleh: Xingbin Hu, Mayra Garcia, Lihong Weng, Xiaoman Jung, Jodi L. Murakami, Bijender Kumar, Charles D. Warden, Ivan Todorov, Ching-Cheng Chen
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-10-01 |
Deskripsi
How the environment of the niche regulates haematopoietic stem cells (HSC) is unclear. Here, the authors identify a mesenchymal stromal progenitor hierarchy and identify Sca1+ cells as common progenitors for mesenchymal stromal cells in the adult niche that provide a supportive environment for hematopoiesis.