Scalable recombinase-based gene expression cascades
oleh: Tackhoon Kim, Benjamin Weinberg, Wilson Wong, Timothy K. Lu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
There are few robust circuit architectures for sequential gene perturbations. Here, the authors use a modular recombinase-based design that sequentially edits loci, synchronizes cells, and deletes itself.