Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish

oleh: Germán Reig, Mauricio Cerda, Néstor Sepúlveda, Daniela Flores, Victor Castañeda, Masazumi Tada, Steffen Härtel, Miguel L. Concha

Format: Article
Diterbitkan: Nature Portfolio 2017-06-01

Deskripsi

The role of mechanical signals in early development are not fully understood. Here, the authors use the simplicity of early killifish embryos to show that tension arising from extra-embryonic epithelial expansion directs the spreading of mesenchymal-like embryonic cells during early morphogenesis.