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Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish
oleh: Germán Reig, Mauricio Cerda, Néstor Sepúlveda, Daniela Flores, Victor Castañeda, Masazumi Tada, Steffen Härtel, Miguel L. Concha
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-06-01 |
Deskripsi
The role of mechanical signals in early development are not fully understood. Here, the authors use the simplicity of early killifish embryos to show that tension arising from extra-embryonic epithelial expansion directs the spreading of mesenchymal-like embryonic cells during early morphogenesis.